Tumour immunology: Feeding frenzy

Nature Reviews Cancer 17, 453 (2017). doi:10.1038/nrc.2017.65 Author: Anna Dart Tumour cells are thought to avoid being phagocytosed through expression of the 'self' marker CD47, which ligates the macrophage receptor SIRPα. Alvey et al. investigated the potential of SIRPα-inhibited bone marrow-derived macrophages, primed with tumour-targeting antibodies, to clear tumours in vivo. Systemic injection
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research