Platelet populations and priming in hematological diseases

In healthy subjects and patients with hematological diseases, platelet populations can be distinguished with different response spectra in hemostatic and vascular processes. These populations appear to partly overlap, and are less distinct than those of leukocytes. The heterogeneity is linked to structural properties, and is enforced by inequalities in the environment. Contributing factors are variability between megakaryocytes, platelet ageing, and positive or negative priming of platelets during their time in circulation.
Source: Blood Reviews - Category: Hematology Authors: Tags: Review Source Type: research