The winding path of protein methylation research: milestones and new frontiers

Nature Reviews Molecular Cell Biology 18, 517 (2017). doi:10.1038/nrm.2017.35 Authors: Jernej Murn & Yang Shi In 1959, while analysing the bacterial flagellar proteins, Ambler and Rees observed an unknown species of amino acid that they eventually identified as methylated lysine. Over half a century later, protein methylation is known to have a regulatory role in many essential cellular processes that
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Perspectives Source Type: research