Tumor immunity requires border patrol to fight the enemy within

Nature Immunology 18, 870 (2017).
doi:10.1038/ni.3792

Authors: Derk Amsen, Pleun Hombrink & Rene A W van Lier
The infiltration of solid tumors by CD8+ T cells is a favorable prognostic marker. Large-scale transcriptome analysis of tumor-infiltrating T cells from mucosal tumors shows that CD8+ T cells with a CD103+ tissue-resident memory T cell phenotype might be the most desirable.

Source: Nature Immunology - July 19, 2017 Category: Allergy & Immunology Authors: Derk Amsen Pleun Hombrink Rene A W van Lier Tags: News and Views Source Type: research