Runx2 ‐I is an Early Regulator of Epithelial–Mesenchymal Cell Transition in the Chick Embryo

Conclusions: These data introduce the RUNX2‐I isoform as a critical early transcription factor mediating EMT in the developing heart after induction by TGFβ2. Its expression in tumor tissue suggests a similar role for RUNX2 in the EMT of metastasis. Developmental Dynamics, 2017. © 2017 Wiley Periodicals, Inc.

Source: Developmental Dynamics - July 19, 2017 Category: Molecular Biology Authors: Andre L.P. Tavares, Jessie A. Brown, Emily C. Ulrich, Katerina Dvorak, Raymond B. Runyan Tags: Research Article Source Type: research