Stand-Alone Pulmonary Vein Isolation Versus Pulmonary Vein Isolation With Additional Substrate Modification as Index Ablation Procedures in Patients With Persistent and Long-Standing Persistent Atrial Fibrillation: The Randomized Alster-Lost-AF Trial (Ablation at St. Georg Hospital for Long-Standing Persistent Atrial Fibrillation) [Original Articles]

Conclusions— In patients with persistent and long-standing persistent atrial fibrillation, no significant difference was observed in 12-month freedom from atrial tachyarrhythmias between an index ablative approach of stand-alone PVI and a stepwise approach of PVI plus complex fractionated atrial electrogram and linear ablation. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00820625.

http://circep.ahajournals.org/cgi/content/short/10/7/e005114?rss=1

Source: Circulation: Arrhythmia and Electrophysiology - July 7, 2017 Category: Cardiology Authors: Fink, T., Schluter, M., Heeger, C.-H., Lemes, C., Maurer, T., Reissmann, B., Riedl, J., Rottner, L., Santoro, F., Schmidt, B., Wohlmuth, P., Mathew, S., Sohns, C., Ouyang, F., Metzner, A., Kuck, K.-H. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator Original Articles Source Type: research