Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure [Original Articles]

Conclusions
Myocardial CTSD upregulation induced by myocardial infarction protects against cardiac remodeling and malfunction, which is at least in part through promoting myocardial autophagic flux.

Source: Circulation: Heart Failure - July 10, 2017 Category: Cardiology Authors: Wu, P., Yuan, X., Li, F., Zhang, J., Zhu, W., Wei, M., Li, J., Wang, X. Tags: Basic Science Research, Myocardial Biology, Chronic Ischemic Heart Disease, Heart Failure, Myocardial Infarction Original Articles Source Type: research