Measurement of the distribution of ventilation-perfusion ratios in the human lung with proton MRI: comparison with the multiple inert-gas elimination technique

We report a comparison of a new proton MRI technique to measure regional VA/Q ratio against the multiple inert gas elimination technique (MIGET). The study reports good relationships between measures of heterogeneity derived from MIGET and those derived from MRI. Although currently limited to a single slice acquisition, these data suggest that single sagittal slice measures of VA/Q ratio provide an adequate means to assess heterogeneity in the normal lung.

Source: Journal of Applied Physiology - July 18, 2017 Category: Physiology Authors: Sa, R. C., Henderson, A. C., Simonson, T., Arai, T. J., Wagner, H., Theilmann, R. J., Wagner, P. D., Prisk, G. K., Hopkins, S. R. Tags: RESEARCH ARTICLE Source Type: research