Global DNA dynamics of 8-oxoguanine repair by human OGG1 revealed by stopped-flow kinetics and molecular dynamic simulation

Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00343A, PaperMaria V. Lukina, Vladimir V. Koval, Alexander A. Lomzov, Dmitry O. Zharkov, Olga S. Fedorova Toxic action of different endogenous and exogenous agents leads to damages in the genomic DNA. 8-Oxoguanine is one of the mostly often generated and highly mutagenic oxidative damage in DNA.... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Molecular Biosystems - July 15, 2017 Category: Molecular Biology Authors: Maria V. Lukina Source Type: research