Complete response of mediastinal clear cell sarcoma to pembrolizumab with radiotherapy

ConclusionThe complete clinical response observed in our patient suggests synergy between concurrent radiotherapy and PD1 blockade in CCS. This case and the striking parallels between CCS and melanoma indicate the need for prospective trials of immune checkpoint blockade combined with radiotherapy in this rare malignancy.
Source: Clinical Sarcoma Research - Category: Cancer & Oncology Source Type: research