Clinical Applications of Small-molecule PET Radiotracers: Current Progress and Future Outlook

Radiotracers, or radiopharmaceuticals, are bioactive molecules tagged with a radionuclide used for diagnostic imaging or radiotherapy and, when a positron-emitting radionuclide is chosen, the radiotracers are used for PET imaging. The development of novel PET radiotracers in many ways parallels the development of new pharmaceuticals, and small molecules dominate research and development pipelines in both disciplines. The 4 decades since the introduction of [18F]FDG have seen the development of many small molecule PET radiotracers.

Source: Seminars in Nuclear Medicine - July 11, 2017 Category: Nuclear Medicine Authors: Amy L. V āvere, Peter J.H. Scott Source Type: research