Neurotoxic Mechanism of Bruceine A Biolarvicide Against Aedes aegypti Linnaeus Larvae

Conclusion: Bruceine A isolated from the seeds of Brucea javanica (L.) Merr. has been demonstrated as biolarvicide against larvae of A. aegypti (L.), through its neurotoxic properties. The mechanism of neurotoxicity is mediated through inhibition of enzyme acetylcholinesterase and VGSC gene.
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research