[Comment] Diagnostic biomarkers for Alzheimer's disease: a regulatory view

Health-care systems worldwide face an unprecedented challenge in dealing with the unmet needs of dementia diagnosis. Dementia is a clinical concept, and the diagnosis of Alzheimer's disease remains essentially based on clinical symptoms, despite the neuropathological end state of the condition being known. Several potential diagnostic biomarkers for Alzheimer's disease have been assessed in cohort studies.1 However, for any disorder, the usefulness of biomarkers is only as good as the understanding of the disease process.

Source: Lancet Neurology - July 12, 2017 Category: Neurology Authors: MT Isaac, S Vamvakas, MB Isaac Tags: Comment Source Type: research