[Comment] Adding insight to injury: a new era in neurotrauma

Traumatic brain injury (TBI) is an age-old disease, and core principles that still guide its management were identified centuries ago. The Edwin –Smith Papyrus describes the use of neurological examinations to classify injury severity, localise lesions, identify intracranial hypertension, triage patients, and predict outcome from as early as 3000–2500 BC.1 Progress in management came in 1744 with the first report of an external ventricul ar drain for CSF diversion,2 and shortly afterwards, the fundamental Monro–Kellie hypothesis was proposed, which described the pressure–volume association between intracranial pressure and the volumes of CSF, blood, and brain tissue in a fixed intracranial space.
Source: Lancet Neurology - Category: Neurology Authors: Tags: Comment Source Type: research