A mouse model of renal cell carcinoma

Nature Medicine 23, 802 (2017). doi:10.1038/nm.4366 Authors: Laura S Schmidt & W Marston Linehan A mouse model with combined renal epithelium-specific deletion of Vhl, Trp53 and Rb1 that develops clear-cell renal cell carcinoma provides a research tool for investigating the mechanisms that drive this cancer, and for evaluating the efficacy of novel therapeutic agents.
Source: Nature Medicine - Category: General Medicine Authors: Tags: News and Views Source Type: research