An unexpected role for bile acid synthesis in adaptation to low temperature

Nature Medicine 23, 800 (2017). doi:10.1038/nm.4365 Authors: Folkert Kuipers & Albert K Groen Enhanced conversion of dietary cholesterol to bile acids through the alternative pathway leads to cold-associated, metabolically beneficial changes in the intestinal microbiome and to elevated bile acid levels that contribute to adaptive thermogenesis.
Source: Nature Medicine - Category: General Medicine Authors: Tags: News and Views Source Type: research