HLA ‐A*02:687, a novel allele identified by sequence‐based typing in cord blood from a Korean woman

Summary statement A*02:687 showed one nucleotide difference with A*02:01:01:01 resulting in an amino acid change. HLA‐A is the second most polymorphic HLA class I gene, with more than 3,900 alleles having been identified according to the IPD‐IMGT/HLA Database (Release 3.28.0, April 2017). 1 In particular, HLA‐A*02 is a very common allotype in the Korean population with a frequency of 28.50%.2 In the Korean population, 11 A*02 alleles have been reported, and A*02:01 is the most frequent.2–5 Here, we report a newly identified A*02:687, a variant of A*02:01:01:01 allele, that was detected in a cord blood unit donated by a Korean woman.
Source: Tissue Antigens - Category: Allergy & Immunology Authors: Tags: NEW ALLELE ALERTS Source Type: research