A FSI computational framework for vascular physiopathology: A novel flow-tissue multiscale strategy

Vascular pathologies are triggered by hemodynamical  [1,2] and biochemical factors [3,4]. As a matter of fact, in the context of Abdominal Aortic Aneurysm (AAA), irregular hemodynamics have been shown to accelerate the progression of such a disease [5,6] with a common basis provided by diabetes, male gender, smoke and hypertension [7]. Moreover, t he imbalance of tissue biochemical pathways drives the onset of pathological remodeling, and thereby of histological alterations affecting vascular mechanics [8].

Source: Medical Engineering and Physics - July 6, 2017 Category: Biomedical Engineering Authors: Daniele Bianchi, Elisabetta Monaldo, Alessio Gizzi, Michele Marino, Simonetta Filippi, Giuseppe Vairo Source Type: research