CFTR-mediated anion secretion across intestinal epithelium-like Caco-2 monolayer under PTH stimulation is dependent on intermediate conductance K+ channels

In conclusion, PTH requires NHE3 and basolateral K+ channels to induce HCO3– and Cl– secretion, thus explaining how PTH regulated luminal pH balance and pH-dependent absorption of trace minerals.

Source: AJP: Cell Physiology - July 6, 2017 Category: Cytology Authors: Jantarajit, W., Lertsuwan, K., Teerapornpuntakit, J., Krishnamra, N., Charoenphandhu, N. Tags: RESEARCH ARTICLE Source Type: research