Does Secretory Clearance Follow Glomerular Filtration Rate in Chronic Kidney Diseases? Reconsidering the Intact Nephron Hypothesis

In conclusion, dosing adjustments in CKD require refinement; in addition to GFR, biomarkers of tubular function are needed for secreted drugs.

Source: Clinical and Translational Science - July 4, 2017 Category: Biomedical Science Authors: A Chapron, DD Shen, BR Kestenbaum, C Robinson ‐Cohen, J Himmelfarb, CK Yeung Tags: ARTICLE Source Type: research