Quantitative Prediction of Paravalvular Leak in Transcatheter Aortic Valve Replacement Based on Tissue-Mimicking 3D Printing

Conclusions
In this proof-of-concept study, we have demonstrated the feasibility of using 3D printed tissue-mimicking phantoms to quantitatively assess the post-TAVR aortic root strain in vitro. A novel indicator of the post-TAVR annular strain unevenness, the annular bulge index, outperformed the other established variables and achieved a high level of accuracy in predicting post-TAVR PVL, in terms of its occurrence, severity, and location.

Source: Journal of the American College of Cardiology: Cardiovascular Imaging - July 3, 2017 Category: Radiology Authors: Qian, Z., Wang, K., Liu, S., Zhou, X., Rajagopal, V., Meduri, C., Kauten, J. R., Chang, Y.-H., Wu, C., Zhang, C., Wang, B., Vannan, M. A. Tags: Original Research Source Type: research