Serum biomarkers for primary graft failure in pediatric heart transplantation

Primary graft failure has been broadly defined as cardiac and circulatory insufficiency in the immediate postoperative period after cardiac transplantation. Risk factors for primary graft failure have been identified in the donor, recipient, and within the perioperative period. Donor serum biomarkers have been identified. The use of donor serum cardiac troponin levels, while most studied, is of questionable value. Basic markers of renal and hepatic function in the recipient are associated with risk of hospital mortality after transplant.
Source: Progress in Pediatric Cardiology - Category: Cardiology Authors: Tags: Review Source Type: research