VO2 kinetics associated with moderate-intensity exercise in heart failure: impact of intrathecal fentanyl inhibition of group III/IV locomotor muscle afferents

This study revealed that abnormal musculoskeletal–neural afferents couple with pulmonary and circulatory dysfunction to provoke impaired exercise Vo2 in HF. Steady-state Vo2 cannot properly phenotype abnormal muscle afferent contributions to impaired exercise Vo2 in HF.

Source: AJP: Heart and Circulatory Physiology - July 1, 2017 Category: Cardiology Authors: Van Iterson, E. H., Johnson, B. D., Joyner, M. J., Curry, T. B., Olson, T. P. Tags: RESEARCH ARTICLE Source Type: research