Shear-mediated dilation of the internal carotid artery occurs independent of hypercapnia

This study further promotes the application and development of hypercapnia as a clinical strategy for the assessment of cerebrovascular vasodilatory function and health in humans. NEW & NOTEWORTHY Shear stress dilates the internal carotid artery in humans. This vasodilatory response occurs independent of other physiological factors, as demonstrated by our transient CO2 test, and is strongly correlated to shear area under the curve. Assessing carotid shear-mediated dilation may provide a future avenue for assessing cerebrovascular health and the risk of cerebrovascular events.

http://ajpheart.physiology.org/cgi/content/abstract/313/1/H24?rss=1

Source: AJP: Heart and Circulatory Physiology - July 1, 2017 Category: Cardiology Authors: Hoiland, R. L., Smith, K. J., Carter, H. H., Lewis, N. C. S., Tymko, M. M., Wildfong, K. W., Bain, A. R., Green, D. J., Ainslie, P. N. Tags: RESEARCH ARTICLE Source Type: research