In vitro and in vivo gene delivery using chitosan/hyaluronic acid nanoparticles: Influences of molecular mass of hyaluronic acid and lyophilization on the transfection efficiency

ConclusionsThe coating of pDNA/chitosan complexes with high‐molecular‐weight HA augmented the stability and cellular transfection ability of the complexes following lyophilization‐rehydration.

Source: The Journal of Gene Medicine - May 1, 2017 Category: Genetics & Stem Cells Authors: Toshinori Sato, Mitsuhiro Nakata, Zhihong Yang, Yu Torizuka, Satoko Kishimoto, Masayuki Ishihara Tags: RESEARCH ARTICLE Source Type: research