Inhibition of mevalonate pathway prevents ischemia ‐induced cardiac dysfunction in rats via RhoA‐independent signaling pathway

ConclusionsThe present findings indicate that mevalonate pathway inhibition by rosuvastatin and alendronate prevent cardiac remodeling and dysfunction possibly through RhoA‐independent mechanisms.This article is protected by copyright. All rights reserved.

Source: Cardiovascular Therapeutics - June 1, 2017 Category: Cardiology Authors: Ying Yang, Xiqing Rong, Xue Lv, Wenbing Jiang, Yuan Yang, Dongwu Lai, Shiming Xu, Guosheng Fu Tags: Original Research Article Source Type: research