Does a Sedation Strategy Including Dexmedetomidine Decrease Mortality and the Need for Mechanical Ventilation in Sepsis?

Synopsis: Septic patients requiring mechanical ventilation did not have decreased mortality or fewer ventilator days if given light sedation that included dexmedetomidine. Source: Kawazoe Y, Miyamoto K, Morimoto T, et al. Effect of dexmedetomidine on mortality and ventilator-free days in patients requiring mechanical ventilation with sepsis (DESIRE). JAMA. 2017;317(13): 1321–1328.
Source: Clinical Pulmonary Medicine - Category: Respiratory Medicine Tags: Pulmonary Trends Source Type: research