Combination of growth pattern and tumor regression identifies a high ‐risk group in neoadjuvant treated rectal cancer patients

CONCLUSIONSLoss of E‐cadherin protein expression in the pretreatment biopsy of rectal cancer is associated with fewer metastases and improved survival. Furthermore, the growth pattern in the post‐RCT resection specimen has a prognostic value for survival. A combination of growth pattern and tumor regression score (the RegPat score) showed the highest discriminatory power to identify high‐risk patients.
Source: Journal of Digestive Diseases - Category: Gastroenterology Authors: Tags: Original Article Source Type: research