Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

Nature Reviews Drug Discovery 16, 457 (2017). doi:10.1038/nrd.2017.23 Authors: Seth W. Dickey, Gordon Y. C. Cheung & Michael Otto The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens are outpacing the development of new antibiotics, but antivirulence agents provide an alternative. These agents can circumvent antibiotic resistance by disarming pathogens of virulence factors that facilitate human disease while leaving bacterial growth pathways
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research