G Protein-Coupled Receptors: Crystal structure of glucagon family receptors

Nature Reviews Drug Discovery 16, 456 (2017). doi:10.1038/nrd.2017.120 Author: Sarah Crunkhorn The class B G protein-coupled receptors (GPCRs), glucagon receptor (GCGR) and glucagon-like peptide 1 receptor (GLP1R), have key roles in glucose homeostasis and therefore represent valuable drug targets for diabetes. Zhang et al. now report the crystal structure of the full-length human GCGR in
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research