Transporters: Natural product provides alternative transport for iron

Nature Reviews Drug Discovery 16, 454 (2017). doi:10.1038/nrd.2017.124 Author: Katie Kingwell Deficiencies in passive ion-transport proteins give rise to a range of diseases, including anaemias, cystic fibrosis and cardiac arrhythmias. A recent paper in Science has demonstrated that a small-molecule natural product, hinokitiol, transports iron across cell membranes and restores iron handling in several animal
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research