The immunopathology of sepsis and potential therapeutic targets

Nature Reviews Immunology 17, 407 (2017).
doi:10.1038/nri.2017.36

Authors: Tom van der Poll, Frank L. van de Veerdonk, Brendon P. Scicluna & Mihai G. Netea
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated host response to infection. In sepsis, the immune response that is initiated by an invading pathogen fails to return to homeostasis, thus culminating in a pathological syndrome that is characterized by

Source: Nature Reviews Immunology - April 24, 2017 Category: Allergy & Immunology Authors: Tom van der Poll Frank L. van de Veerdonk Brendon P. Scicluna Mihai G. Netea Tags: Review Source Type: research