Resveratrol prevents the combined maternal plus post-weaning high-fat diets induced hypertension in male offspring
Maternal high-fat (HF) diet is believed to induce oxidative stress and activate nutrient-sensing signals, which increases the risk of adult offspring to develop hypertension. We investigated whether resveratrol prevents the combined maternal plus post-weaning HF diets-induced hypertension in adult male offspring, with a focus on the kidney. Female Sprague –Dawley rats received either a normal diet (ND) or HF diet (D12331, Research Diets) for 5 weeks before mating and during gestation and lactation.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: You-Lin Tain, Yu-Ju Lin, Jiunn-Ming Sheen, I-Chun Lin, Hong-Ren Yu, Li-Tung Huang, Chien-Ning Hsu Source Type: research