Finite-element design and optimization of a three-dimensional tetrahedral porous titanium scaffold for the reconstruction of mandibular defects

Mandible defects usually result from trauma, tumor resection, or osteomyelitis. Unrepaired defects can lead to disturbed masticatory function, loss of speech, and facial deformity, which can seriously affect the patient's quality of life. Thus, timely reconstruction is necessary, but remains a challenge [1]. The goal of mandibular reconstruction is to restore both the shape and function of the mandible. To date, many mandibular reconstruction methods have evolved, such as free bone grafts, pedicled bone grafts, particulate bone cancellous marrow, microvascular free flaps, modular endoprosthesis, and tissue engineered bone [2].
Source: Medical Engineering and Physics - Category: Biomedical Engineering Authors: Source Type: research