Expression of miR-23a induces telomere shortening and is associated with poor clinical outcomes in patients with coronary artery disease

In conclusion, elevated levels of miR-23a play an important role in coronary atherosclerosis via downregulated TRF2, and may provide important prognostic information in patients with CAD. Additionally, aggressive LLT may prevent telomere erosion via downregulated miR-23a.

Source: Clinical Science - June 23, 2017 Category: Biomedical Science Authors: Satoh, M., Nasu, T., Takahashi, Y., Osaki, T., Hitomi, S., Morino, Y., Nakamura, M. Tags: PublishAheadOfPrint Source Type: research