An Assessment of Database-Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis

Conclusions:
Our data suggest that miRNA target gene databases are incomplete; pathways derived from these databases have similar deficiencies. Although we know a lot about several miRNAs, little is known about other miRNAs in terms of their targeted genes. We encourage others to use their data to continue to further identify and validate miRNA-targeted genes.

Source: Cancer Informatics - June 23, 2017 Category: Cancer & Oncology Authors: Martha L Slattery Jennifer S Herrick John R Stevens Roger K Wolff Lila E Mullany Source Type: research