Leukaemia: Unravelling the heterogeneity of cancer stem cells
Nature Reviews Cancer 17, 397 (2017).
doi:10.1038/nrc.2017.44
Author: Sarah Seton-Rogers
Giustacchini, Thongjuea, et al. have developed a method to sensitively detect somatic mutations and analyze whole transcriptomes of the same single cell. Application of this technique to chronic myeloid leukaemia (CML) patient samples revealed heterogeneous CML stem cell populations with likely roles in CML progression and resistance to therapy.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Sarah Seton-Rogers Tags: Research Highlight Source Type: research
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