Leukaemia: Unravelling the heterogeneity of cancer stem cells

Nature Reviews Cancer 17, 397 (2017). doi:10.1038/nrc.2017.44 Author: Sarah Seton-Rogers Giustacchini, Thongjuea, et al. have developed a method to sensitively detect somatic mutations and analyze whole transcriptomes of the same single cell. Application of this technique to chronic myeloid leukaemia (CML) patient samples revealed heterogeneous CML stem cell populations with likely roles in CML progression and resistance to therapy.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research