Immunotherapy: Macrophages steal the show

Nature Reviews Cancer 17, 396 (2017). doi:10.1038/nrc.2017.47 Author: M. Teresa Villanueva Pittet and collaborators show that macrophages can remove anti-PD1 antibodies from T cells, blunting their response, whereas Weissman and colleagues demonstrate that macrophages also express PD1 on their surface, which impairs their phagocytic activity.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research