Obesity and menopause modify the epigenomic profile of breast cancer

In conclusion, the epigenome of breast tumors is affected by a complex interaction between BMI and menopausal status. The ZNF577 methylation quantification is clearly relevant for the development of novel biomarkers of precision therapy in breast cancer.

Source: Endocrine-Related Cancer - June 22, 2017 Category: Endocrinology Authors: Crujeiras, A. B., Diaz-Lagares, A., Stefansson, O. A., Macias-Gonzalez, M., Sandoval, J., Cueva, J., Lopez-Lopez, R., Moran, S., Jonasson, J. G., Tryggvadottir, L., Olafsdottir, E., Tinahones, F. J., Carreira, M. C., Casanueva, F. F., Esteller, M. Tags: Research Source Type: research