Association of mitochondrial DNA in peripheral blood with depression, anxiety and stress- and adjustment disorders in primary health care patients

The objectives here were to examine possible differences in mtDNA copy number between healthy controls and patients with depression, anxiety or stress- and adjustment disorders; the association between mtDNA copy number and disease severity at baseline; and the association between mtDNA copy number and response after an 8-week treatment (mindfulness, cognitive based therapy). A total of 179 patients in primary health care (age 20 –64 years) with depression, anxiety and stress- and adjustment disorders, and 320 healthy controls (aged 19–70 years) were included in the study.

Source: European Neuropsychopharmacology - June 21, 2017 Category: Psychiatry & Psychology Authors: Xiao Wang, Kristina Sundquist, Hamideh Rastkhani, Karolina Palm ér, Ashfaque A. Memon, Jan Sundquist Source Type: research