EB virus reactivation triggers thrombotic thrombocytopenic purpura in a healthy adult

Publication date: Available online 20 June 2017 Source:Leukemia Research Reports Author(s): Satoko Oka, Masaharu Nohgawa Thrombotic thrombocytopenic purpura (TTP) is rare but life-threatening disease, characterized typically by microangiopathic hemolytic anemia (MAHA), profound peripheral thrombocytopenia and severe deficiency in the von Willebrand factor-cleaving prortease ADAMTS13. It has been reported that acquired immune TTP is closely associated with human immunodeficiency virus infection and influenza infection or vaccination. However, it has not been reported to be associated with Epstein Barr Virus infection or reactivation. We herein report a first case of acquired TTP associated with EBV reactivation in an otherwise healthy adult.
Source: Leukemia Research Reports - Category: Hematology Source Type: research