Bladder Cancer and Water Disinfection By-product Exposures through Multiple Routes: A Population-Based Case –Control Study (New England, USA)

Conclusions:
We observed a modest association between ingestion of water with higher THMs (>95th percentile vs.<25th percentile) and bladder cancer. Brominated THMs have been a particular concern based on toxicologic evidence, and our suggestive findings for multiple metrics require further study in a population with higher levels of these exposures. Data from this population do not support an association between swimming pool use and bladder cancer. https://doi.org/10.1289/EHP89

Received: 09 March 2016
Revised: 27 October 2016
Accepted: 28 October 2016
Published: 21 June 2017
Address correspondence to L. Beane Freeman, 9609 Medical Center Dr., Rm 6E136, MSC 9771, Bethesda, MD 20892. Telephone: [phone]. Email: [e-mail]
Supplemental Material is available online (https://doi.org/10.1289/EHP89).
J.R.N. is an Emeritus and Adjunct faculty at Colorado State University and is self-employed by JRN-Environmental Health Sciences. K.P.C. was formally with the Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI). He has performed work under contract to KP Cantor, LLC, and subcontract to the NCI.
All other authors declare they have no actual or potential competing financial interests.
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Source: EHP Research - June 21, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research