A rheostat tuning thymic selection

Nature Immunology 18, 713 (2017). doi:10.1038/ni.3778 Authors: Gerald P Morris & Stephen M Hedrick Thymocytes must undergo positive selection to survive and differentiate. This process is regulated by the TCR-sensitive protein CHMPS by preventing Bcl2 oxidation and degradation.
Source: Nature Immunology - Category: Allergy & Immunology Authors: Tags: News and Views Source Type: research