A rheostat tuning thymic selection
Nature Immunology 18, 713 (2017).
doi:10.1038/ni.3778
Authors: Gerald P Morris & Stephen M Hedrick
Thymocytes must undergo positive selection to survive and differentiate. This process is regulated by the TCR-sensitive protein CHMPS by preventing Bcl2 oxidation and degradation.
Source: Nature Immunology - Category: Allergy & Immunology Authors: Gerald P Morris Stephen M Hedrick Tags: News and Views Source Type: research
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