Neurodevelopmental disorders: Taking on FXS with a diabetes drug

Nature Reviews Neuroscience 18, 387 (2017). doi:10.1038/nrn.2017.80 Author: Darran Yates Fragile X syndrome (FXS) is characterized by learning disabilities and behavioural problems and is linked to dysregulated mRNA translation. Here, the authors treated a mouse model of FXS with the type 2 diabetes drug metformin, which, among other effects, suppresses translation. Metformin treatment rescued various
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Research Highlight Source Type: research