A case of pure gelastic seizures due to hypothalamic hamartoma with a benign course

We report a case of gelastic seizures associated with a hypothalamic hamartoma, which followed a benign course. A 31-year-old woman with episodes of laughter was referred for diagnostic evaluation. Her initial MRI and EEG were reported as normal. However, her laughter episodes were typical of gelastic seizures from history and video. Repeat MRI revealed a small HH. She declined any medical treatment and was medication free until last follow up. This benign course of HH-associated epilepsy, not necessitating treatment, to our knowledge, has not been previously reported.

Source: Epilepsy and Behavior Case Reports - June 17, 2017 Category: Neurology Source Type: research