Oral Lymphomatoid papulosis type C: A diagnostic pitfall, often confused with T-cell lymphoma

Eosinophilic ulcer of the oral mucosa (EUOM) is a rare, benign, self-resolving lymphoproliferative disorder, which typically presents with asymptomatic to mildly tender ulcers. Histological findings of EUOM are characterized by a polymorphic infiltrate with many eosinophils often extending into the underlying muscle. Although this entity is well documented within the dental literature, it is not well known to physicians. The pathogenesis of the condition is unclear, although reports dating back to 1997 suggest that at least a subset of EUOM represents CD30 positive lymphoproliferative disorder (LPD30).

Source: Annals of Diagnostic Pathology - June 16, 2017 Category: Pathology Authors: Ziv Schwartz, Morton Coleman, Jennifer P. Toyohara, Paul D. Freedman, Cynthia M. Magro Source Type: research