The influence of antidepressants on restless legs syndrome and periodic limb movements: A systematic review
Restless legs syndrome is commonly co-morbid with medical conditions that are treated with antidepressant medications, such as depression, anxiety, fibromyalgia, and chronic insomnia disorder. Evidence from case reports and cross-sectional studies suggests that antidepressants may induce or worsen restless legs syndrome and increase periodic limb movements. We undertook a systematic review of the literature to identify and collate all prospective studies that measured restless legs syndrome symptoms and/or periodic limb movements following the introduction of an antidepressant.
Source: Sleep Medicine Reviews - Category: Sleep Medicine Authors: Bhanu Prakash Kolla, Meghna P. Mansukhani, J. Michael Bostwick Tags: Clinical Review Source Type: research
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