Individual and Joint Effects of Early-Life Ambient PM2.5 Exposure and Maternal Prepregnancy Obesity on Childhood Overweight or Obesity

Conclusions:
In the present study, we observed that early life exposure to PM2.5 may play an important role in the early life origins of COWO and may increase the risk of COWO in children of mothers who were overweight or obese before pregnancy beyond the risk that can be attributed to MPBMI alone. Our findings emphasize the clinical and public health policy relevance of early life PM2.5 exposure. https://doi.org/10.1289/EHP261

Received: 29 March 2016
Revised: 08 August 2016
Accepted: 23 August 2016
Published: 14 June 2017
Address correspondence to X. Wang, Center on the Early Life Origins of Disease, Department of Population, Family and Reproductive Health, Johns Hopkins University Bloomberg School of Public Health, Johns Hopkins University School of Medicine, 615 N. Wolfe Street, E4132, Baltimore, MD 21205-2179, Phone [phone], E-mail [e-mail]
Supplemental Material is available online (https://doi.org/10.1289/EHP261).
*These authors contributed equally to this work.
The authors declare they have no actual or potential competing financial interests.
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Source: EHP Research - June 14, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research