Elevated Levels of Coagulation Factor VIII in Patients With Venous Leg Ulcers

We report 3 patients with chronic leg ulcers and high levels of FVIII:C activity in plasma and other associated thrombophilic factors. We highlight the need to get a workup done for thrombophilia in young patients with recurrent and chronic leg ulcers related to venous insufficiency or livedoid vasculopathy. Further studies with larger sample sizes are required to define the definite indications for the thrombophilia workups.

Source: The International Journal of Lower Extremity Wounds - June 13, 2014 Category: Surgery Authors: Criado, P. R., Alavi, A., Kirsner, R. S. Tags: Case Report Source Type: research