Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction [Original Articles]

Conclusions—
Global run-on sequencing allowed us to follow the gradient of gene expression occurring in the ischemic heart and identify novel noncoding RNAs regulated by oxygen deprivation. These findings highlight potential new targets for diagnosis and treatment of myocardial ischemia.

Source: Circulation: Cardiovascular Genetics - June 13, 2017 Category: Cardiology Authors: Kaikkonen, M. U., Halonen, P., Liu, O. H.-F., Turunen, T. A., Pajula, J., Moreau, P., Selvarajan, I., Tuomainen, T., Aavik, E., Tavi, P., Yla-Herttuala, S. Tags: Animal Models of Human Disease, Ischemia, Gene Expression & Regulation, Myocardial Infarction Original Articles Source Type: research